Description

4-Chloro-7-Fluoro-2-Methylquinazoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive chlorination and fluorination sites, which enable precise molecular modifications for creating novel compounds with targeted properties. This intermediate is critically needed by research and development teams in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Serves as a building block for creating specialty chemicals, dyes, and advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploring new chemical entities.
• Custom Synthesis: A versatile starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	4-Chloro-7-Fluoro-2-Methylquinazoline
CAS No.	1206694-32-7
Molecular Formula	C9H6ClFN2
Molecular Weight	196.61 g/mol
Synonyms	4-Chloro-7-fluoro-2-methylquinazoline; 2-Methyl-4-chloro-7-fluoroquinazoline; 7-Fluoro-4-chloro-2-methylquinazoline; Quinazoline, 4-chloro-7-fluoro-2-methyl-; 1206694-32-7; 4-Chloro-7-fluoro-2-methyl-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Fluoro-2-Methylquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.