Description

Methyl 3-(1,2,3,4-Tetrahydro-2,4-Dioxo-1,8-Naphthyridin-3-Yl)Propanoate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation drugs targeting complex diseases, ensuring process consistency and regulatory compliance from early development to commercial scale.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, especially those with naphthyridine-based core structures.
• API Synthesis: Used in research and production of Active Pharmaceutical Ingredients (APIs) for potential applications in oncology, antiviral, and central nervous system (CNS) therapeutics.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable manufacturing of target molecules.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for advanced material science and agrochemical research.

Basic Information

Item	Detail
Product Name	Methyl 3-(1,2,3,4-Tetrahydro-2,4-Dioxo-1,8-Naphthyridin-3-Yl)Propanoate
CAS No.	1206679-93-7
Molecular Formula	C12H12N2O4
Molecular Weight	248.24 g/mol
Synonyms	Methyl 3-(1,2,3,4-tetrahydro-2,4-dioxo-1,8-naphthyridin-3-yl)propionate; 3-(1,2,3,4-Tetrahydro-2,4-dioxo-1,8-naphthyridin-3-yl)propanoic acid methyl ester; 1,8-Naphthyridine-3-propanoic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester; Methyl 3-(2,4-dioxo-1,2,3,4-tetrahydro-1,8-naphthyridin-3-yl)propanoate; CAS 1206679-93-7
EINECS	Contact for details

Quality Control

Our Methyl 3-(1,2,3,4-Tetrahydro-2,4-Dioxo-1,8-Naphthyridin-3-Yl)Propanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.