Description

4-Amino-6-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic combination of a quinoline scaffold with amino, trifluoromethyl, and ester functionalities, enabling the construction of complex molecules with tailored properties. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-infectives, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science: Used in the research of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient quinoline core.
• Chemical Biology Probe Development: Employed as a building block for creating fluorescent tags or molecular probes to study biological processes.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	4-Amino-6-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1206108-53-3
Molecular Formula	C₁₃H₁₁F₃N₂O₂
Molecular Weight	284.24 g/mol
Synonyms	Ethyl 4-Amino-6-(trifluoromethyl)quinoline-3-carboxylate; 4-Amino-6-trifluoromethyl-3-quinolinecarboxylic Acid Ethyl Ester; 6-(Trifluoromethyl)-4-aminoquinoline-3-carboxylic Acid Ethyl Ester; 4-Amino-6-(trifluoromethyl)-3-quinolinecarboxylic Acid, Ethyl Ester; AQCE; 1206108-53-3; Ethyl 4-amino-6-(trifluoromethyl)quinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Amino-6-(Trifluoromethyl)Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.