Description

4-Amino-6,8-Difluoroquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotics and other biologically active quinoline derivatives.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the difluoroquinoline scaffold.
• Chemical Research & Development: Serves as a versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production of complex drug molecules targeting bacterial infections and other therapeutic areas.
• Material Science: Potential intermediate for the synthesis of organic electronic materials and fluorescent dyes due to the quinoline core.

Basic Information

Product Name	4-Amino-6,8-Difluoroquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1206092-20-7
Molecular Formula	C₁₂H₁₀F₂N₂O₂
Molecular Weight	252.22 g/mol
Synonyms	Ethyl 4-Amino-6,8-difluoroquinoline-3-carboxylate; 6,8-Difluoro-4-aminoquinoline-3-carboxylic Acid Ethyl Ester; 4-Amino-6,8-difluoro-3-quinolinecarboxylic Acid Ethyl Ester; 1206092-20-7; 4-Amino-6,8-difluoroquinoline-3-carboxylate ethyl ester; Ethyl 4-amino-6,8-difluoro-3-quinolinecarboxylate; AI3-63542
EINECS	Contact for details

Quality Control

Our 4-Amino-6,8-Difluoroquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.