Description

7-Amino-2,3-Dihydro-1,4,-Benzoxazepine 1,1-Dimethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its benzoxazepine core structure, which is of significant interest in modern medicinal chemistry. This compound matters because it serves as a critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop new active pharmaceutical ingredients (APIs) with potential improved efficacy and safety profiles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzoxazepine-based drug candidates for CNS research.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for constructing complex molecules in the final stages of API synthesis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and pharmacological mechanisms.
• Process Chemistry: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	7-Amino-2,3-Dihydro-1,4,-Benzoxazepine 1,1-Dimethyl Ester
CAS No.	1205750-08-8
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	1,1-Dimethyl 7-Amino-2,3-dihydro-1,4-benzoxazepine-4,5-dicarboxylate; 7-Amino-1,1-dimethyl 2,3-dihydro-1H-1,4-benzoxazepine-4,5-dicarboxylate; 1H-1,4-Benzoxazepine-4,5-dicarboxylic acid, 7-amino-2,3-dihydro-1,1-dimethyl ester; 7-Amino-2,3-dihydro-1,4-benzoxazepine-1,1-dicarboxylic acid dimethyl ester; 1205750-08-8; Amino benzoxazepine diester; Dimethyl 7-amino-2,3-dihydro-1,4-benzoxazepine-1,1-dicarboxylate
EINECS	Contact for details

Quality Control

Our 7-Amino-2,3-Dihydro-1,4,-Benzoxazepine 1,1-Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are provided with every shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.