Description

1-Boc-3-Hydrazinylpyrrolidine is a high-purity, protected heterocyclic building block essential for advanced organic synthesis. This compound is valued for its dual functional groups, which enable its use as a versatile intermediate in constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those containing pyrrolidine and hydrazine pharmacophores.
• Peptidomimetics & Macrocycle Synthesis: Used to introduce constrained ring systems and hydrazide linkages into peptide backbones for drug discovery.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Agrochemical Research: Utilized as a building block in the development of new herbicides and fungicides with novel modes of action.
• Academic & Process R&D: A valuable reagent for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	1-Boc-3-Hydrazinylpyrrolidine
CAS No.	1205557-00-1
Molecular Formula	C9H19N3O2
Molecular Weight	201.27 g/mol
Synonyms	tert-Butyl 3-hydrazinylpyrrolidine-1-carboxylate; 3-Hydrazinyl-1-(tert-butoxycarbonyl)pyrrolidine; 1-Boc-3-hydrazinopyrrolidine; 1-N-Boc-3-hydrazinopyrrolidine; Pyrrolidine, 3-hydrazinyl-1-[(1,1-dimethylethoxy)carbonyl]-; 1-(tert-Butoxycarbonyl)-3-hydrazinylpyrrolidine; Boc-3-hydrazinopyrrolidine
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Hydrazinylpyrrolidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.