Description

2-Phenyl-6-Trifluoromethoxyquinolin-4-Ol is a high-value, multi-functional quinoline derivative characterized by its unique phenyl and trifluoromethoxy substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a core scaffold for developing new-generation pesticides and herbicides with enhanced efficacy.
• Organic Light-Emitting Diodes (OLEDs): Serves as an electron-transport or host material in the fabrication of high-performance optoelectronic devices.
• Ligand in Catalysis: Acts as a sophisticated ligand for transition metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Fluorescent Probe Synthesis: Building block for creating sensitive chemical sensors and bio-imaging agents due to its inherent fluorophore properties.
• Material Science: Incorporated into advanced polymers and coatings to impart specific chemical resistance or optical properties.

Basic Information

Product Name	2-Phenyl-6-Trifluoromethoxyquinolin-4-Ol
CAS No.	1204997-08-9
Molecular Formula	C₁₇H₁₀F₃NO₂
Molecular Weight	317.26 g/mol
Synonyms	4-Hydroxy-2-phenyl-6-(trifluoromethoxy)quinoline; 6-(Trifluoromethoxy)-2-phenylquinolin-4-ol; 2-Phenyl-6-(trifluoromethoxy)-4-quinolinol; 4-Quinolinol, 2-phenyl-6-(trifluoromethoxy)-; 2-Phenyl-6-trifluoromethoxy-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 2-Phenyl-6-Trifluoromethoxyquinolin-4-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.