Description

3-Chloro-4-Hydroxy-8-Methylquinoline is a halogenated hydroxyquinoline derivative, a versatile and high-value organic building block. This compound matters for its role as a key synthetic intermediate in the development of advanced pharmaceuticals and functional materials. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly for antimicrobial, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and pesticides, leveraging the bioactive quinoline scaffold.
• Coordination Chemistry & Chelating Agent: Acts as a ligand for metal ions, useful in catalysis and the preparation of metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other functional organic materials.
• Chemical Synthesis Building Block: Provides a multifunctional platform for further chemical modifications, including etherification, esterification, and cross-coupling reactions.

Basic Information

Product Name	3-Chloro-4-Hydroxy-8-Methylquinoline
CAS No.	1204812-35-0
Molecular Formula	C₁₀H₈ClNO
Molecular Weight	193.63 g/mol
Synonyms	8-Methyl-3-chloro-4-quinolinol; 3-Chloro-8-methylquinolin-4-ol; 4-Hydroxy-3-chloro-8-methylquinoline; 3-Chloro-4-hydroxy-8-methylquinoline; 8-Methyl-3-chloro-4-hydroxyquinoline; 3-Chloro-8-methyl-4-quinolinol; Quinoline, 3-chloro-4-hydroxy-8-methyl-
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Hydroxy-8-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.