Description

4-Bromo-8-Fluoro-2-Propylquinoline Hydrobromide is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is valued for its unique halogenated quinoline structure, which is critical for constructing complex molecules in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for applications in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Organic Synthesis Reagent: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to introduce the quinoline scaffold into more complex structures.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides due to its bioactive quinoline core.
• Material Science: Potential use in the synthesis of organic semiconductors and light-emitting materials for electronic applications.
• Academic & R&D: Essential for chemical research in universities and corporate labs focusing on heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	4-Bromo-8-Fluoro-2-Propylquinoline Hydrobromide
CAS No.	1204812-29-2
Molecular Formula	C₁₂H₁₂BrFN•HBr
Molecular Weight	359.05 g/mol
Synonyms	4-Bromo-8-fluoro-2-propylquinoline hydrobromide; 8-Fluoro-4-bromo-2-propylquinoline HBr; Quinoline, 4-bromo-8-fluoro-2-propyl-, hydrobromide; 2-Propyl-4-bromo-8-fluoroquinoline hydrobromide; 4-Bromo-8-fluoro-2-propylquinoline HBr salt
EINECS	Contact for details

Quality Control

Our 4-Bromo-8-Fluoro-2-Propylquinoline Hydrobromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.