Description

3-Bromo-4,5-Dichloro-8-Methoxyquinoline is a high-purity, multi-substituted quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an invaluable intermediate for developing novel pharmaceuticals and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of antimicrobial, antiviral, and anticancer agents targeting quinoline-based pharmacophores.
• Agrochemical Research: Used in the design and synthesis of new-generation pesticides, herbicides, and fungicides, leveraging its halogenated quinoline core for bioactivity.
• Material Science: Serves as a monomer or functional additive in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Synthesis: An essential reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to the reactive bromo and chloro substituents.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Dye & Pigment Industry: Acts as a precursor for synthesizing specialized quinoline-based dyes and fluorescent markers.

Basic Information

Product Name	3-Bromo-4,5-Dichloro-8-Methoxyquinoline
CAS No.	1204812-28-1
Molecular Formula	C₁₀H₆BrCl₂NO
Molecular Weight	307.97 g/mol
Synonyms	8-Methoxy-3-bromo-4,5-dichloroquinoline; 4,5-Dichloro-3-bromo-8-methoxyquinoline; 3-Bromo-4,5-dichloro-8-methoxy-quinoline; Quinoline, 3-bromo-4,5-dichloro-8-methoxy-; 1204812-28-1
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4,5-Dichloro-8-Methoxyquinoline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.