Description

3-Bromo-4-Chloro-8-Trifluoromethoxyquinoline is a high-purity, multi-functional halogenated quinoline derivative, engineered for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering significant value in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used to construct advanced active ingredients for crop protection products, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for functional organic materials, including organic light-emitting diodes (OLEDs) and charge-transport layers.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromo and chloro substituents.
• Ligand & Catalyst Development: Employed in the design of novel chelating ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3-Bromo-4-Chloro-8-Trifluoromethoxyquinoline
CAS No.	1204812-16-7
Molecular Formula	C₁₁H₄BrClF₃NO
Molecular Weight	340.51 g/mol
Synonyms	8-(Trifluoromethoxy)-3-bromo-4-chloroquinoline; 3-Bromo-4-chloro-8-(trifluoromethoxy)quinoline; Quinoline, 3-bromo-4-chloro-8-(trifluoromethoxy)-; 1204812-16-7; 3-Br-4-Cl-8-OCF3-quinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-8-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.