Description

3,4-Dichloro-8-Fluoroquinoline is a high-purity fluorinated and chlorinated quinoline derivative, serving as a critical advanced pharmaceutical intermediate. Its unique halogenated structure makes it a valuable scaffold for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of antimicrobial and anticancer agents. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides with enhanced activity.
• Organic Synthesis Research: A versatile reagent for constructing complex heterocyclic compounds in academic and industrial R&D settings.
• Material Science Precursor: Potential intermediate for the development of organic electronic materials and functional dyes.
• Chemical Biology Probes: Serves as a core structure for developing fluorescent probes or enzyme inhibitors for biochemical research.

Basic Information

Product Name	3,4-Dichloro-8-Fluoroquinoline
CAS No.	1204811-28-8
Molecular Formula	C9H4Cl2FN
Molecular Weight	216.04 g/mol
Synonyms	8-Fluoro-3,4-dichloroquinoline; 3,4-Dichloro-8-fluoroquinoline; Quinoline, 3,4-dichloro-8-fluoro-; 1204811-28-8
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-8-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.