Description

3-Chloro-6-Ethoxy-4-Hydroxyquinoline is a high-purity quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those with quinoline-based pharmacophores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science: Serves as a precursor for organic semiconductors, ligands for metal complexes, and other functional organic materials.
• Chemical Synthesis: Versatile intermediate for further functionalization, enabling the creation of diverse chemical libraries for screening.
• Academic & R&D: Essential reagent for methodological studies in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	3-Chloro-6-Ethoxy-4-Hydroxyquinoline
CAS No.	1204811-22-2
Molecular Formula	C₁₁H₁₀ClNO₂
Molecular Weight	223.66 g/mol
Synonyms	4-Hydroxy-3-chloro-6-ethoxyquinoline; 6-Ethoxy-3-chloro-4-hydroxyquinoline; 3-Chloro-6-ethoxyquinolin-4-ol; 3-Chloro-4-hydroxy-6-ethoxyquinoline; Quinoline, 3-chloro-6-ethoxy-4-hydroxy-; 1204811-22-2 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Ethoxy-4-Hydroxyquinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.