Description

4-Chloro-8-Fluoro-2-Propylquinoline Hydrochloride is a high-purity, halogenated quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile chemical building block for the development of novel active compounds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing kinase inhibitors or antimicrobial agents.
• Agrochemical Research: Used as a building block for creating new active ingredients in crop protection products, such as herbicides or fungicides.
• Chemical Synthesis: Serves as a versatile scaffold in organic chemistry for constructing complex heterocyclic compounds due to its reactive halogen and nitrogen sites.
• Material Science: Potential application in the development of organic electronic materials or advanced ligands for catalytic systems.
• Biochemical Research: May be used in the development of fluorescent probes or molecular tags for biological imaging and diagnostics.

Basic Information

Product Name	4-Chloro-8-Fluoro-2-Propylquinoline Hydrochloride
CAS No.	1204811-15-3
Molecular Formula	C₁₂H₁₂ClFN•HCl
Molecular Weight	260.59 g/mol (Free base: 223.68 g/mol)
Synonyms	4-Chloro-8-fluoro-2-propylquinoline hydrochloride; 2-Propyl-4-chloro-8-fluoroquinoline hydrochloride; 4-Chloro-8-fluoro-2-propylquinoline HCl; 4-Chloro-8-fluoro-2-n-propylquinoline hydrochloride; Quinoline, 4-chloro-8-fluoro-2-propyl-, hydrochloride (1:1); CAS 1204811-15-3
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-Fluoro-2-Propylquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is between 2°C and 8°C (refrigerated). Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.