Description

3-Bromo-4-Chloro-8-Fluoroquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules with tailored biological and material properties. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, crop protection, and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antibacterial and antiviral agents, leveraging the bioactive quinoline core.
• Agrochemical Research: Used in developing next-generation fungicides and herbicides, where the halogen pattern enhances biological activity and environmental stability.
• Organic Synthesis: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex heterocyclic libraries for screening.
• Material Science: Investigated as a monomer or dopant for creating organic semiconductors and light-emitting materials due to its electron-deficient aromatic system.
• Chemical Biology: Utilized as a molecular probe or tag in bioconjugation and target identification studies.

Basic Information

Product Name	3-Bromo-4-Chloro-8-Fluoroquinoline
CAS No.	1204810-96-7
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	8-Fluoro-3-bromo-4-chloroquinoline; 4-Chloro-3-bromo-8-fluoroquinoline; Quinoline, 3-bromo-4-chloro-8-fluoro-; 1204810-96-7; 3-Bromo-4-chloro-8-fluoro-quinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-8-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.