Description

4-Hydrazino-5,8-Difluoroquinoline Hydrochloride is a high-purity, functionalized quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic incorporation of both hydrazine and fluorine substituents, which are essential for modulating the biological activity and physicochemical properties of target molecules. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer, where the quinoline scaffold is prevalent.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging the bioactivity of the fluorinated quinoline structure.
• Chemical Biology Probe Synthesis: Employed to create specialized molecular probes for studying enzyme mechanisms or protein interactions in biological systems.
• Material Science Research: Serves as a starting material for synthesizing complex organic ligands used in catalysis or for creating novel fluorophores in optical materials.
• Contract Research & Development (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and process chemistry projects.

Basic Information

Product Name	4-Hydrazino-5,8-Difluoroquinoline Hydrochloride
CAS No.	1204810-91-2
Molecular Formula	C9H6F2N3·HCl
Molecular Weight	231.62 g/mol (Free base: 195.16)
Synonyms	5,8-Difluoro-4-hydrazinylquinoline Hydrochloride; 4-Hydrazinyl-5,8-difluoroquinoline Hydrochloride; 5,8-Difluoro-4-hydrazinoquinoline HCl; 4-Hydrazino-5,8-difluoroquinoline HCl; 1204810-91-2; 4-Hydrazino-5,8-difluoroquinoline monohydrochloride
EINECS	Contact for details

Quality Control

Our 4-Hydrazino-5,8-Difluoroquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and moisture uptake. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	95.0% - 105.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.