Description

3,4-Dichloro-7-Trifluoromethoxyquinoline is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound matters for its critical role in the synthesis of complex molecules, particularly in medicinal chemistry for developing new active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, agrochemical manufacturers, and pharmaceutical companies engaged in the discovery and production of novel quinoline-based therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides with the trifluoromethoxy moiety offering enhanced biological activity and stability.
• Material Science: Serves as a specialized building block for creating organic electronic materials and functional dyes.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex heterocyclic systems for various R&D applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	3,4-Dichloro-7-Trifluoromethoxyquinoline
CAS No.	1204810-90-1
Molecular Formula	C₁₀H₄Cl₂F₃NO
Molecular Weight	282.05 g/mol
Synonyms	7-(Trifluoromethoxy)-3,4-dichloroquinoline; 3,4-Dichloro-7-(trifluoromethoxy)quinoline; Quinoline, 3,4-dichloro-7-(trifluoromethoxy)-; 1204810-90-1
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-7-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.