Description

3-Chloro-4-Hydroxy-7-Trifluoromethoxyquinoline is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is valued for its unique molecular scaffold, which is critical for synthesizing novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used as a core building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Organic Synthesis & Research: Serves as a versatile scaffold in academic and industrial research for constructing novel heterocyclic compounds and exploring structure-activity relationships (SAR).
• Material Science Precursor: Potential use in the development of advanced organic electronic materials and functional dyes due to its quinoline-based structure.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Chloro-4-Hydroxy-7-Trifluoromethoxyquinoline
CAS No.	1204810-76-3
Molecular Formula	C₁₁H₅ClF₃NO₂
Molecular Weight	275.61 g/mol
Synonyms	3-Chloro-4-hydroxy-7-(trifluoromethoxy)quinoline; 7-(Trifluoromethoxy)-3-chloroquinolin-4-ol; 3-Chloro-4-hydroxy-7-trifluoromethoxyquinoline; 4-Quinolinol, 3-chloro-7-(trifluoromethoxy)-; 3-Chloro-7-trifluoromethoxy-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Hydroxy-7-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.