Description

3-Bromo-6,8-Dimethyl-4-Hydroxyquinoline is a halogenated quinoline derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique bromo-hydroxy-dimethyl substitution pattern makes it a critical building block for constructing complex molecular architectures with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer, where the quinoline scaffold is pharmacologically active.
• Agrochemical Research: Used in the development of new fungicides, herbicides, or pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating organic ligands in catalysis or for synthesizing advanced organic electronic materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine atom, enabling the introduction of complex substituents.
• Coordination Chemistry: Acts as a chelating agent for metal ions, useful in creating metal-organic frameworks (MOFs) or catalytic complexes.
• Fluorescent Probe Development: The quinoline core can be modified to create dyes or sensors for biological or environmental detection applications.

Basic Information

Product Name	3-Bromo-6,8-Dimethyl-4-Hydroxyquinoline
CAS No.	1204810-75-2
Molecular Formula	C11H10BrNO
Molecular Weight	252.11 g/mol
Synonyms	4-Hydroxy-3-bromo-6,8-dimethylquinoline; 6,8-Dimethyl-3-bromo-4-quinolinol; 3-Bromo-6,8-dimethylquinolin-4-ol; 3-Bromo-6,8-dimethyl-4-quinolinol; 4-Quinolinol, 3-bromo-6,8-dimethyl-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and precise customer requirements. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all critical quality attributes. Our quality management system is designed to support research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.