Description

4-Hydrazino-6,8-Difluoroquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluoroquinoline scaffold. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antibacterial and anticancer agents. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for its role in creating next-generation therapeutics, where its specific substitution pattern enables targeted molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone-based antibiotics targeting resistant bacterial strains.
• Anticancer Drug Development: Used in research and production of small-molecule inhibitors and targeted therapies due to the quinoline core's affinity for various enzyme targets.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents with enhanced efficacy and environmental profile.
• Material Science Research: Employed in the creation of specialized organic ligands and fluorinated compounds for advanced material applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	4-Hydrazino-6,8-Difluoroquinoline Hydrochloride
CAS No.	1204810-72-9
Molecular Formula	C9H7ClF2N3
Molecular Weight	230.62 g/mol
Synonyms	6,8-Difluoro-4-hydrozinylquinoline hydrochloride; 4-Hydrazinyl-6,8-difluoroquinoline hydrochloride; Quinoline, 4-hydrazino-6,8-difluoro-, hydrochloride; 6,8-Difluoro-4-hydrazinoquinoline HCl; 4-Hydrazino-6,8-difluoroquinoline HCl; 1204810-72-9; 4-Hydrazino-6,8-difluoroquinoline monohydrochloride
EINECS	Contact for details

Quality Control

Our 4-Hydrazino-6,8-Difluoroquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.