Description

3-Bromo-8-Ethyl-4-Hydroxyquinoline is a halogenated quinoline derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique bromo- and hydroxy-substituted quinoline structure makes it a critical building block for constructing complex molecules with tailored biological and material properties. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, ligand synthesis, and the development of functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, such as fungicides and herbicides.
• Coordination Chemistry & Ligand Synthesis: Acts as a chelating ligand or precursor for metal-organic frameworks (MOFs) and catalysts due to its hydroxyquinoline core.
• Material Science: Building block for organic electronic materials, including OLEDs and sensors, where its bromine atom facilitates further cross-coupling reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent probes or enzyme inhibitors for biochemical research.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	3-Bromo-8-Ethyl-4-Hydroxyquinoline
CAS No.	1204810-69-4
Molecular Formula	C₁₁H₁₀BrNO
Molecular Weight	252.11 g/mol
Synonyms	4-Hydroxy-3-bromo-8-ethylquinoline; 8-Ethyl-3-bromo-4-hydroxyquinoline; 3-Bromo-8-ethylquinolin-4-ol; 4-Quinolinol, 3-bromo-8-ethyl-; 1204810-69-4
EINECS	Contact for details

Quality Control

Our 3-Bromo-8-Ethyl-4-Hydroxyquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.