Description

3-Bromo-4,5-Dichloro-8-Methylquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique halogen substitution pattern, which provides distinct reactivity and electronic properties for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, catalyst development, and the synthesis of novel functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobials, and other biologically active quinoline-based compounds.
• Agrochemical Research: Used as a versatile scaffold for creating new active ingredients in crop protection agents, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functional unit in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Catalyst & Ligand Synthesis: Employed in the preparation of specialized nitrogen-containing ligands for transition metal catalysis.
• Chemical Biology: Utilized as a molecular probe or tag due to its distinct spectroscopic signature and reactivity.
• Academic & Industrial R&D: Fundamental building block for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	3-Bromo-4,5-Dichloro-8-Methylquinoline
CAS No.	1204810-68-3
Molecular Formula	C₁₀H₆BrCl₂N
Molecular Weight	291.97 g/mol
Synonyms	8-Methyl-3-bromo-4,5-dichloroquinoline; 4,5-Dichloro-3-bromo-8-methylquinoline; Quinoline, 3-bromo-4,5-dichloro-8-methyl-; 3-Bromo-4,5-dichloro-8-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-4,5-Dichloro-8-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.