Description

3,4-Dichloro-8-Trifluoromethoxyquinoline is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), offering unique reactivity due to its halogenated and fluorinated substituents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel quinoline-based drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethoxy group can improve metabolic stability and lipophilicity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Fluorinated Compound Library: An essential reagent for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3,4-Dichloro-8-Trifluoromethoxyquinoline
CAS No.	1204810-63-8
Molecular Formula	C₁₀H₄Cl₂F₃NO
Molecular Weight	282.05 g/mol
Synonyms	8-(Trifluoromethoxy)-3,4-dichloroquinoline; 3,4-Dichloro-8-(trifluoromethoxy)quinoline; Quinoline, 3,4-dichloro-8-(trifluoromethoxy)-; 1204810-63-8
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-8-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.