Description

3,4-Dichloro-6-Trifluoromethylquinoline is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of halogen and trifluoromethyl substituents, which are pivotal for modulating the electronic, lipophilic, and metabolic properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and other biologically active small molecules.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioavailability and efficacy.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as charge-transport layers or luminescent compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	3,4-Dichloro-6-Trifluoromethylquinoline
CAS No.	1204810-59-2
Molecular Formula	C10H4Cl2F3N
Molecular Weight	266.05 g/mol
Synonyms	6-(Trifluoromethyl)-3,4-dichloroquinoline; 3,4-Dichloro-6-(trifluoromethyl)quinoline; Quinoline, 3,4-dichloro-6-(trifluoromethyl)-; 1204810-59-2
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-6-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.