Description

3,6-Dichloro-4-Hydroxy-8-Methylquinoline is a halogenated quinoline derivative that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a valuable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as fungicides and herbicides, leveraging its bioactive quinoline core.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for synthesizing electron-transport or emissive layer materials in electronic displays and lighting.
• Coordination Chemistry & Ligand Synthesis: The hydroxy and chloro groups provide sites for metal chelation, useful in creating catalysts or metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized quinoline-derived colorants and fluorescent markers.
• Academic and Industrial R&D: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies in medicinal chemistry.

Basic Information

Product Name	3,6-Dichloro-4-Hydroxy-8-Methylquinoline
CAS No.	1204810-48-9
Molecular Formula	C₁₀H₇Cl₂NO
Molecular Weight	228.08 g/mol
Synonyms	4-Hydroxy-3,6-dichloro-8-methylquinoline; 8-Methyl-3,6-dichloro-4-quinolinol; 3,6-Dichloro-8-methyl-4-quinolinol; 4-Quinolinol, 3,6-dichloro-8-methyl-; 3,6-Dichloro-4-hydroxy-8-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 3,6-Dichloro-4-Hydroxy-8-Methylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.