Description

3-Bromo-4-Chloro-6-Methylquinoline is a halogenated quinoline derivative, a versatile and high-value organic building block prized for its unique reactivity profile. This compound is essential for advanced research and development in medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobials, and other biologically active heterocyclic compounds.
• Agrochemical Research: Serves as a core scaffold for designing and synthesizing new-generation pesticides, herbicides, and fungicides with improved efficacy and selectivity.
• Material Science: Used in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and charge-transport layers, due to the quinoline core's electronic properties.
• Chemical Synthesis: Functions as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other metal-catalyzed transformations to construct complex molecular architectures.
• Ligand & Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline-based dyes and fluorescent markers.

Basic Information

Product Name	3-Bromo-4-Chloro-6-Methylquinoline
CAS No.	1204810-41-2
Molecular Formula	C10H7BrClN
Molecular Weight	256.53 g/mol
Synonyms	6-Methyl-3-bromo-4-chloroquinoline; 4-Chloro-3-bromo-6-methylquinoline; 3-Bromo-4-chloro-6-methyl-quinoline; Quinoline, 3-bromo-4-chloro-6-methyl-; 1204810-41-2; 3-Br-4-Cl-6-Me-quinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-6-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.