Description

2-Propyl-4,5,8-Trichloroquinoline Hydrochloride is a specialized quinoline derivative salt, primarily utilized as a high-value synthetic intermediate in advanced organic chemistry. Its core value proposition lies in its unique halogenated structure, which makes it a critical building block for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a building block for developing advanced pesticides, herbicides, and fungicides due to its halogenated quinoline core.
• Material Science Research: Used in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic routes in heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-Propyl-4,5,8-Trichloroquinoline Hydrochloride
CAS No.	1204810-38-7
Molecular Formula	C₁₂H₁₁Cl₃N•HCl
Molecular Weight	313.04 g/mol (Free base)
Synonyms	4,5,8-Trichloro-2-propylquinoline Hydrochloride; 2-n-Propyl-4,5,8-trichloroquinoline HCl; 4,5,8-Trichloro-2-propylquinoline Hydrochloride Salt; Quinoline, 4,5,8-trichloro-2-propyl-, hydrochloride; 1204810-38-7; 2-Propyl-4,5,8-trichloroquinoline monohydrochloride
EINECS	Contact for details

Quality Control

Our 2-Propyl-4,5,8-Trichloroquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.