Description

3-Bromo-4-Chloro-6,8-Difluoroquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of antimicrobial and anticancer agents.
• Agrochemical Synthesis: Used to construct complex heterocyclic cores for next-generation herbicides, fungicides, and pesticides.
• Material Science Research: Serves as a functional monomer or ligand in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed as a scaffold for creating fluorescent tags or enzyme inhibitors for biochemical research.
• Catalyst Ligand Development: The quinoline structure can be modified to create novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific halogenated quinoline motifs.

Basic Information

Product Name	3-Bromo-4-Chloro-6,8-Difluoroquinoline
CAS No.	1204810-25-2
Molecular Formula	C9H3BrClF2N
Molecular Weight	278.48 g/mol
Synonyms	3-Bromo-4-chloro-6,8-difluoroquinoline; 6,8-Difluoro-3-bromo-4-chloroquinoline; Quinoline, 3-bromo-4-chloro-6,8-difluoro-; 1204810-25-2; 3-Br-4-Cl-6,8-F-Quinoline; 4-Chloro-3-bromo-6,8-difluoroquinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-6,8-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment ensures material integrity for your most demanding research and development and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.