Description

3-Bromo-4,6-Dichloro-8-Methoxyquinoline is a high-value, multi-halogenated quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its precise molecular architecture makes it indispensable for constructing complex heterocyclic frameworks, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scalable synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, antimalarials, and kinase inhibitors.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and pesticides where the quinoline core provides specific biological activity.
• Material Science Precursor: Serves as a starting material for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and photoactive compounds.
• Chemical Biology Probe: Utilized in medicinal chemistry to study structure-activity relationships (SAR) and for labeling or modifying biomolecules.
• Catalyst & Ligand Synthesis: Acts as a precursor for synthesizing specialized nitrogen-containing ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and process R&D.

Basic Information

Product Name	3-Bromo-4,6-Dichloro-8-Methoxyquinoline
CAS No.	1204810-12-7
Molecular Formula	C10H6BrCl2NO
Molecular Weight	307.97 g/mol
Synonyms	8-Methoxy-3-bromo-4,6-dichloroquinoline; 4,6-Dichloro-3-bromo-8-methoxyquinoline; 3-Bromo-4,6-dichloro-8-methoxy-quinoline; Quinoline, 3-bromo-4,6-dichloro-8-methoxy-; BDDMQ
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4,6-Dichloro-8-Methoxyquinoline is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets a typical purity specification of ≥95% (by HPLC), with higher purity grades available. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for assay, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.