Description

3-Bromo-4,7,8-Trichloroquinoline is a halogenated quinoline derivative, a versatile and high-value organic building block prized for its unique reactivity profile. This compound is essential for advanced synthetic chemistry, particularly in the development of complex molecules for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and material science sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides due to its bioactive quinoline core.
• Material Science Research: Serves as a building block for creating functionalized organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Cross-Coupling Reactions: The bromine and chlorine substituents make it an excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Heterocyclic Chemistry: A fundamental starting material for the preparation of more complex polycyclic and fused heterocyclic systems.

Basic Information

Product Name	3-Bromo-4,7,8-Trichloroquinoline
CAS No.	1204810-10-5
Molecular Formula	C9H3BrCl3N
Molecular Weight	315.39 g/mol
Synonyms	4,7,8-Trichloro-3-bromoquinoline; 3-Bromo-4,7,8-trichloroquinoline; Quinoline, 3-bromo-4,7,8-trichloro-; 1204810-10-5; SCHEMBL21880227; ZINC000095909786; AKOS040759395; CTK8J5115
EINECS	Contact for details

Quality Control

Our 3-Bromo-4,7,8-Trichloroquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods include HPLC, GC, NMR, and MS to verify specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.