Description

3,4-Dichloro-8-Trifluoromethylquinoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular architecture, featuring both halogen and trifluoromethyl substituents, makes it a critical intermediate for the development of novel active compounds. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a versatile building block for the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core and halogen atoms.
• Material Science Research: Used in the development of advanced organic materials, including organic light-emitting diodes (OLEDs) and electronic chemicals, due to its electron-deficient quinoline structure.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in chemical probe development for studying biological systems and protein function.
• Organic Synthesis & Catalysis: Acts as a precursor or ligand in catalytic reactions and cross-coupling chemistry to construct more complex molecular architectures.

Basic Information

Product Name	3,4-Dichloro-8-Trifluoromethylquinoline
CAS No.	1204810-08-1
Molecular Formula	C10H4Cl2F3N
Molecular Weight	266.05 g/mol
Synonyms	8-(Trifluoromethyl)-3,4-dichloroquinoline; 3,4-Dichloro-8-(trifluoromethyl)quinoline; Quinoline, 3,4-dichloro-8-(trifluoromethyl)-; 1204810-08-1; 3,4-Dichloro-8-trifluoromethyl-quinoline
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-8-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.