Description

3,4-Dichloro-6-Trifluoromethoxyquinoline is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines halogenated and trifluoromethoxy substituents to impart significant electronic and steric properties, making it a critical intermediate in the development of novel active ingredients. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents with enhanced efficacy and patentability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a core building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science Research: Used in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient character.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chelating ligands for catalytic applications.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	3,4-Dichloro-6-Trifluoromethoxyquinoline
CAS No.	1204810-06-9
Molecular Formula	C₁₀H₄Cl₂F₃NO
Molecular Weight	282.05 g/mol
Synonyms	6-(Trifluoromethoxy)-3,4-dichloroquinoline; 3,4-Dichloro-6-(trifluoromethoxy)quinoline; Quinoline, 3,4-dichloro-6-(trifluoromethoxy)-; 1204810-06-9; 3,4-Dichloro-6-trifluoromethoxy-quinoline
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-6-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to consistent quality and traceability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.