Description

8-Bromo-3-Chloro-4-Hydroxy-6-Methylquinoline is a halogenated quinoline derivative, a versatile and high-value synthetic intermediate in advanced organic chemistry. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and functional materials due to its reactive bromo and chloro substituents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in antimicrobial, anticancer, and CNS-targeted research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the quinoline scaffold's bioactivity.
• Material Science Precursor: Serves as a starting material for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and photoactive compounds.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions to introduce complex functionalities.
• Dye and Pigment Intermediate: Acts as a precursor in the synthesis of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	8-Bromo-3-Chloro-4-Hydroxy-6-Methylquinoline
CAS No.	1204810-02-5
Molecular Formula	C₁₀H₇BrClNO
Molecular Weight	272.53 g/mol
Synonyms	8-Bromo-3-chloro-4-hydroxy-6-methylquinoline; 6-Methyl-8-bromo-3-chloro-4-quinolinol; 4-Hydroxy-8-bromo-3-chloro-6-methylquinoline; 3-Chloro-8-bromo-4-hydroxy-6-methylquinoline; Quinoline, 8-bromo-3-chloro-4-hydroxy-6-methyl-; 1204810-02-5 (CAS)
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-Chloro-4-Hydroxy-6-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.