Description

3-Chloro-7,8-Difluoro-4-Hydroxyquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated quinoline structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel antibacterial and antiviral agents, particularly fluoroquinolone derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging its halogenated quinoline core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in electronic applications.
• Coordination Chemistry & Ligand Synthesis: Acts as a chelating agent for metal ions in catalytic systems and material science research.
• Fluorescent Probe Development: Utilized in creating sensitive chemical sensors and bio-imaging agents due to its fluorophore potential.
• Academic & Industrial R&D: A valuable compound for medicinal chemistry programs and process development in fine chemical manufacturing.

Basic Information

Product Name	3-Chloro-7,8-Difluoro-4-Hydroxyquinoline
CAS No.	1204810-01-4
Molecular Formula	C9H4ClF2NO
Molecular Weight	215.59 g/mol
Synonyms	4-Hydroxy-3-chloro-7,8-difluoroquinoline; 7,8-Difluoro-3-chloro-4-quinolinol; 3-Chloro-7,8-difluoroquinolin-4-ol; 4-Quinolinol, 3-chloro-7,8-difluoro-; 3-Cl-7,8-F2-4-OH-Quinoline
EINECS	Contact for details

Quality Control

Our 3-Chloro-7,8-Difluoro-4-Hydroxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.