Description

8-Aza-Bicyclo[3.2.1]Oct-2-Ene-3,8-Dicarboxylic Acid 8-tert-Butyl Ester is a sophisticated bicyclic organic compound that serves as a critical building block in advanced organic synthesis. Its unique bridged structure and protected carboxylic acid functionality make it a valuable intermediate for constructing complex nitrogen-containing molecules. This high-purity compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for medicinal chemists developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the pharmacokinetic properties of lead compounds.
• Agrochemical Development: Serves as a precursor in the creation of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Academic & Institutional R&D: Employed in university and research institute laboratories for fundamental studies in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	8-Aza-Bicyclo[3.2.1]Oct-2-Ene-3,8-Dicarboxylic Acid 8-tert-Butyl Ester
CAS No.	1204809-89-1
Molecular Formula	C13H19NO4
Molecular Weight	253.30 g/mol
Synonyms	8-Azabicyclo[3.2.1]oct-2-ene-3,8-dicarboxylic acid 8-(1,1-dimethylethyl) ester; 8-tert-Butyl 8-azabicyclo[3.2.1]oct-2-ene-3,8-dicarboxylate; 8-Aza-Bicyclo[3.2.1]Oct-2-Ene-3,8-Dicarboxylic Acid 8-tert-Butyl Ester; 8-tert-Butyl 3,8-diazabicyclo[3.2.1]octane-3,8-dicarboxylate (common misnomer); 8-Azabicyclo[3.2.1]oct-2-ene-3-carboxylic acid, 8-(tert-butoxycarbonyl)-; 1204809-89-1; tert-Butyl 8-azabicyclo[3.2.1]oct-2-ene-8-carboxylate-3-carboxylate
EINECS	Contact for details

Quality Control

Our 8-Aza-Bicyclo[3.2.1]Oct-2-Ene-3,8-Dicarboxylic Acid 8-tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.