Description

1-(2-Bromo-4-Chlorophenyl)Cyclopropanamine Hcl is a high-purity, advanced pharmaceutical intermediate featuring a unique halogenated cyclopropylamine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics. It is an essential building block for medicinal chemistry research and pharmaceutical manufacturing, where precise molecular architecture is required to modulate biological activity and improve drug efficacy.

Application

• Pharmaceutical Intermediate: A key synthon in the research and commercial-scale synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities (NCEs).
• API Development: Serves as a crucial precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents and pesticides.
• Academic & Institutional Research: Utilized in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	1-(2-Bromo-4-Chlorophenyl)Cyclopropanamine Hydrochloride
CAS No.	1204580-93-7
Molecular Formula	C9H10BrClN • HCl
Molecular Weight	293.45 g/mol (Free base: 256.54 g/mol)
Synonyms	1-(2-Bromo-4-chlorophenyl)cyclopropanamine hydrochloride; 1-(2-Bromo-4-chlorophenyl)cyclopropanamine HCl; 2-Bromo-4-chloro-α-(cyclopropylamino)toluene hydrochloride; Cyclopropanamine, 1-(2-bromo-4-chlorophenyl)-, hydrochloride; 1-(2-Bromo-4-chloro-phenyl)-cyclopropylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-4-Chlorophenyl)Cyclopropanamine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.