Description

6-Bromoquinazoline-4-Carbonitrile is a high-value brominated quinazoline derivative, a crucial heterocyclic building block in modern synthetic chemistry. Its core value lies in its versatile reactivity, serving as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other targeted therapeutic agents, particularly in oncology research.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging the bioactive quinazoline scaffold.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating tool compounds to study enzyme function and cellular pathways.
• Material Science Research: Employed in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized quinazoline cores.
• Academic & R&D Laboratories: Used in methodological studies and discovery chemistry for novel organic transformations.

Basic Information

Item	Details
Product Name	6-Bromoquinazoline-4-Carbonitrile
CAS No.	1204334-27-9
Molecular Formula	C9H4BrN3
Molecular Weight	234.05 g/mol
Synonyms	4-Cyano-6-bromoquinazoline; 6-Bromo-4-quinazolinecarbonitrile; Quinazoline-4-carbonitrile, 6-bromo-; 6-Bromoquinazoline-4-carbonitrile; 1204334-27-9; 6-Bromo-quinazoline-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Bromoquinazoline-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical data are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.