Description

2',4',5',7' - Tetrahydrospiro[[1,3]Dioxolane - 2,6' - Indazole] (CAS NO 1204218-41-6) is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic indazole-dioxolane structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new lead structures.
• Organic Synthesis Building Block: Employed in complex organic transformations, leveraging its reactive sites for further functionalization to create novel chemical entities.
• Biochemical Tool Compound: Utilized in academic and industrial research to study biological mechanisms and validate new therapeutic targets.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client-sponsored projects.

Basic Information

Product Name	2',4',5',7' - Tetrahydrospiro[[1,3]Dioxolane - 2,6' - Indazole]
CAS No.	1204218-41-6
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	2',4',5',7'-Tetrahydrospiro[1,3-dioxolane-2,6'-indazole]; Spiro[1,3-dioxolane-2,6'-indazole], 2',4',5',7'-tetrahydro-; Tetrahydrospiro[dioxolane-indazole]; 1,3-Dioxolane-2-spiro-6'-2',4',5',7'-tetrahydroindazole; 6'-Indazole, 2',4',5',7'-tetrahydrospiro[1,3-dioxolane-2,6'-]; Research Code Intermediate 1204218-41-6
EINECS	Contact for details

Quality Control

Our production of 2',4',5',7' - Tetrahydrospiro[[1,3]Dioxolane - 2,6' - Indazole] adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures a reliable supply for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.