Description

2-Bromo-4-Chloro-5-(Trifluoromethyl)Phenol is a halogenated phenol derivative that serves as a versatile and high-value synthetic intermediate in advanced chemical manufacturing. Its unique structure, featuring bromine, chlorine, and trifluoromethyl substituents, makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial chemists working in the development of pharmaceuticals and agrochemicals, where it is used to introduce specific halogenated motifs that can enhance biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for halogenated mesogens used in the production of advanced display technologies.
• Polymer Chemistry: Acts as a monomer or chain modifier for engineering plastics and high-performance polymers, imparting flame retardancy and chemical resistance.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex aromatic systems, facilitating Suzuki-Miyaura and other cross-coupling reactions.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized halogenated dyes and pigments for niche industrial applications.

Basic Information

Product Name	2-Bromo-4-Chloro-5-(Trifluoromethyl)Phenol
CAS No.	1203898-21-8
Molecular Formula	C7H3BrClF3O
Molecular Weight	275.45 g/mol
Synonyms	2-Bromo-4-chloro-α,α,α-trifluoro-m-cresol; 5-Bromo-3-chloro-2-hydroxybenzotrifluoride; Phenol, 2-bromo-4-chloro-5-(trifluoromethyl)-; 3-Bromo-1-chloro-2-hydroxy-5-(trifluoromethyl)benzene; 2-Hydroxy-3-bromo-5-chlorobenzotrifluoride; 4-Chloro-2-bromo-5-(trifluoromethyl)phenol
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-5-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.