Description

1,8-Diazaspiro[5.5]Undecan-7-One is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class of heterocyclic compounds. This compound is valued for its unique three-dimensional structure, which serves as a critical building block in modern medicinal chemistry for creating novel molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients, particularly in programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key scaffold in the research and synthesis of new drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used as a versatile building block to explore structure-activity relationships (SAR) and improve the pharmacokinetic properties of lead compounds.
• Agrochemical Development: Employed in the creation of novel pesticides and herbicides, leveraging its spirocyclic structure for enhanced biological activity.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds and probes to study biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized fine chemicals and APIs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1,8-Diazaspiro[5.5]Undecan-7-One
CAS No.	1203798-24-6
Molecular Formula	C9H14N2O
Molecular Weight	166.22 g/mol
Synonyms	1,8-Diazaspiro[5.5]undecan-7-one; 7H-1,8-Diazaspiro[5.5]undecan-7-one; Spiro[piperidine-4,2'-pyrrolidin]-3-one; 1,8-Diazaspiro[5.5]undecane-7-one; UNII-8J7A9Q8Z4W; 8J7A9Q8Z4W; AOB67717; AKOS025310923; ZINC00025310923; SCHEMBL15506227; DTXSID60654388
EINECS	Contact for details

Quality Control

Our 1,8-Diazaspiro[5.5]Undecan-7-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.