Description

(S)-(Tetrahydro-2H-Pyran-3-Yl)Methanamine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold essential for constructing complex molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, process development, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• API Synthesis: Incorporated into the synthetic pathway of complex Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in catalytic asymmetric transformations.
• Agrochemical Research: Employed in the discovery and synthesis of new chiral pesticides and herbicides where stereochemistry affects efficacy.
• Academic & Contract Research: Used in university and CRO (Contract Research Organization) laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	(S)-(Tetrahydro-2H-Pyran-3-Yl)Methanamine Hydrochloride
CAS No.	1203706-83-5
Molecular Formula	C6H14ClNO
Molecular Weight	151.63 g/mol
Synonyms	(S)-3-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; (S)-Tetrahydro-2H-pyran-3-ylmethanamine hydrochloride; (S)-(3-Pyranyl)methylamine hydrochloride; (S)-Aminomethyl-tetrahydropyran hydrochloride; (S)-3-Pyranmethanamine, tetrahydro-, hydrochloride; (S)-Tetrahydropyran-3-ylmethylamine HCl; (S)-3-(Aminomethyl)tetrahydropyran HCl
EINECS	Contact for details

Quality Control

Our (S)-(Tetrahydro-2H-Pyran-3-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.