Description

(2S,3R,4R,5S)-3,4,5-Tris(Phenylmethoxy)-2-[(Phenylmethoxy)Methyl]-1-(2-Propen-1-Yl)-Piperidine is a high-purity, advanced pharmaceutical intermediate characterized by its complex stereochemistry and multiple benzyl-protected hydroxyl groups. This compound matters for its critical role as a sophisticated building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in antiviral and neurological drug discovery. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug molecules, especially nucleoside analogs and other bioactive compounds.
• Antiviral Drug Research: Used in the research and development of novel antiviral agents, leveraging its piperidine scaffold for targeted activity.
• Neurological & CNS Drug Discovery: Acts as a precursor in the synthesis of potential therapeutics targeting neurological disorders and central nervous system (CNS) pathways.
• Process Chemistry & Scale-Up: Employed in process development and optimization for the commercial-scale manufacturing of APIs requiring this specific stereoisomer.
• Academic & Institutional Research: Utilized in academic settings for methodological studies in asymmetric synthesis, protecting group chemistry, and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A critical component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services for client-specific molecules.

Basic Information

Product Name	(2S,3R,4R,5S)-3,4,5-Tris(Phenylmethoxy)-2-[(Phenylmethoxy)Methyl]-1-(2-Propen-1-Yl)-Piperidine
CAS No.	1203659-55-5
Molecular Formula	C37H41NO4
Molecular Weight	563.73 g/mol
Synonyms	1-Allyl-2,3,4-tris-O-benzyl-6-O-benzyl-myo-inositol derivative (piperidine form); 1-Allyl-2,3,4-tris-O-benzyl-6-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol; 1,5-Dideoxy-1,5-imino-2,3,4,6-tetra-O-benzyl-1-N-allyl-D-glucitol; Tetra-O-benzyl-1-N-allyl-deoxynojirimycin derivative; Protected 1-Allyl-deoxynojirimycin; Allyl-DNJ tetra-benzyl ether; CAS 1203659-55-5
EINECS	Contact for details

Quality Control

Our (2S,3R,4R,5S)-3,4,5-Tris(Phenylmethoxy)-2-[(Phenylmethoxy)Methyl]-1-(2-Propen-1-Yl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for stereochemical purity and identity confirmation by NMR and mass spectrometry, to ensure compliance with stringent research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.