Description

5-(tert-Butoxycarbonyl)Pyridine-3-Boronic Acid is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors, where precise molecular structure is critical.
• Chemical Biology Probes: Useful for constructing bioconjugates and molecular probes for target identification and validation in biological systems.
• Custom Synthesis and Contract Manufacturing: A vital reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	5-(tert-Butoxycarbonyl)Pyridine-3-Boronic Acid
CAS No.	1203649-61-9
Molecular Formula	C11H16BNO4
Molecular Weight	237.06 g/mol
Synonyms	3-Borono-5-[(tert-butoxy)carbonyl]pyridine; 5-(Boc)pyridine-3-boronic acid; (5-((tert-Butoxycarbonyl)pyridin-3-yl)boronic acid; tert-Butyl 5-borononicotinate; 3-Pyridineboronic acid, 5-[(1,1-dimethylethoxy)carbonyl]-; Boc-protected 3-pyridylboronic acid; 5-Carboxytert-butoxypyridine-3-boronic Acid (protected form)
EINECS	Contact for details

Quality Control

Every batch of 5-(tert-Butoxycarbonyl)Pyridine-3-Boronic Acid is manufactured and tested under strict quality management systems to ensure consistency and reliability for critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and reactivity. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.