Description

4-Amino-3-Chloro-7-Trifluoromethylquinoline is a high-value, multi-functional heterocyclic building block. This compound is engineered to serve as a critical intermediate in the synthesis of advanced, high-performance molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries, where its unique trifluoromethyl-substituted quinoline scaffold enables the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and fungicides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a building block for creating specialty chemicals, dyes, and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs developing proprietary compounds for clients.

Basic Information

Product Name	4-Amino-3-Chloro-7-Trifluoromethylquinoline
CAS No.	1203579-71-8
Molecular Formula	C₁₀H₆ClF₃N₂
Molecular Weight	246.62 g/mol
Synonyms	3-Chloro-4-amino-7-(trifluoromethyl)quinoline; 7-(Trifluoromethyl)-3-chloroquinolin-4-amine; 4-Amino-3-chloro-7-(trifluoromethyl)quinoline; 3-Chloro-7-trifluoromethyl-4-aminoquinoline; Quinoline, 4-amino-3-chloro-7-(trifluoromethyl)-; 4-AQ-3C-7TFMQ
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-7-Trifluoromethylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical specifications. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.