Description

3,4-Dichloro-7-Trifluoromethylquinoline is a high-value, multi-functional heterocyclic building block. This compound is prized for its unique molecular scaffold, which combines a quinoline core with halogen and trifluoromethyl substituents, making it a critical intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients. Its structural features are leveraged to modulate the biological activity, metabolic stability, and physicochemical properties of target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used to develop new generations of herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Acts as a building block for creating advanced organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Utilized in the design of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Fluorescent Probe Synthesis: The quinoline fluorophore is modified to create sensitive chemical sensors and biological imaging agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific R&D programs.

Basic Information

Product Name	3,4-Dichloro-7-Trifluoromethylquinoline
CAS No.	1203579-58-1
Molecular Formula	C10H4Cl2F3N
Molecular Weight	266.05 g/mol
Synonyms	7-(Trifluoromethyl)-3,4-dichloroquinoline; 3,4-Dichloro-7-(trifluoromethyl)quinoline; Quinoline, 3,4-dichloro-7-(trifluoromethyl)-; 3,4-Dichloro-7-trifluoromethyl-quinoline
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-7-Trifluoromethylquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.