Description

1-tert-Butyl-6-Iodo-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One is a high-value, halogenated heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for medicinal chemistry research and development, serving as a key intermediate in the synthesis of novel pharmaceutical candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific structural motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of potential drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical space.
• Agrochemical Synthesis: Serves as a precursor in the development of new active ingredients for crop protection.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.
• Academic Research: Employed in university and institutional labs for methodological development and novel heterocycle chemistry.

Basic Information

Product Name	1-tert-Butyl-6-Iodo-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One
CAS No.	1203499-26-6
Molecular Formula	C11H13IN2O2
Molecular Weight	332.14 g/mol
Synonyms	1-(tert-Butyl)-6-iodo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one; 6-Iodo-1-(tert-butyl)-1H,2H,3H-pyrido[2,3-b][1,4]oxazin-2-one; 1-tert-Butyl-6-iodo-3H-pyrido[2,3-b][1,4]oxazin-2-one; tert-Butyl 6-iodo-2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-1-carboxylate (common misnomer); 1203499-26-6; 1H-Pyrido[2,3-b][1,4]oxazin-2(3H)-one, 1-(1,1-dimethylethyl)-6-iodo-
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl-6-Iodo-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.