Description

3-Aminocyclopentanecarboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant chiral building block. This compound is a key intermediate in the synthesis of complex molecules, particularly for drug discovery and development programs targeting neurological and metabolic disorders. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disease research.
• Peptidomimetics & Constrained Peptides: Used to introduce a rigid, cyclopentane backbone into peptide structures to enhance metabolic stability and receptor selectivity.
• Chemical Biology Probes: Serves as a building block for creating tool compounds and probes to study enzyme function and biological pathways.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in catalytic asymmetric reactions to construct stereochemically complex molecules.
• Agrochemical Research: Potential intermediate in the development of new herbicides or plant growth regulators with specific chiral activity.
• Academic & Contract Research: Supplied to universities and CROs for fundamental organic chemistry research and custom synthesis projects.

Basic Information

Product Name	3-Aminocyclopentanecarboxylic Acid Hydrochloride
CAS No.	1203306-05-1
Molecular Formula	C6H12ClNO2
Molecular Weight	165.62 g/mol
Synonyms	3-Aminocyclopentane-1-carboxylic acid hydrochloride; (1R,3S)-3-Aminocyclopentanecarboxylic acid hydrochloride; (1S,3R)-3-Aminocyclopentanecarboxylic acid hydrochloride; 3-ACPC HCl; Cycloleucine derivative; 3-Amino-1-cyclopentanecarboxylic acid HCl; cis-3-Aminocyclopentanecarboxylic acid hydrochloride; trans-3-Aminocyclopentanecarboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Aminocyclopentanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomer excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.