Description

6,7-Dihydro-5H-Pyrrolo[2,1-C][1,2,4]Triazol-3-Methylamine. 3Hcl is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern medicinal chemistry. This compound matters for its role as a key precursor in the synthesis of novel, biologically active molecules, particularly within heterocyclic chemistry. Pharmaceutical R&D and fine chemical synthesis laboratories need this material to develop new therapeutic agents, leveraging its unique fused triazole-pyrrolidine scaffold.

Application

• Pharmaceutical Intermediate: Critical building block for the research and development of new active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for identifying novel drug candidates.
• Bioconjugation & Probe Development: The amine functional group allows for conjugation, making it useful in creating biochemical probes and targeted delivery systems.
• Agrochemical Synthesis: Serves as a precursor in the development of new generation pesticides and herbicides with specific biological activity.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with unique electronic or thermal properties.

Basic Information

Product Name	6,7-Dihydro-5H-Pyrrolo[2,1-C][1,2,4]Triazol-3-Methylamine. 3Hcl
CAS No.	1203258-81-4
Molecular Formula	C7H13Cl3N4
Molecular Weight	259.56 g/mol
Synonyms	3-(Aminomethyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazole trihydrochloride; 6,7-Dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-ylmethanamine trihydrochloride; 3-(Aminomethyl)-5H,6H,7H-pyrrolo[2,1-c][1,2,4]triazole hydrochloride (1:3); Pyrrolotriazole-3-methylamine trihydrochloride; CAS 1203258-81-4
EINECS	Contact for details

Quality Control

Our 6,7-Dihydro-5H-Pyrrolo[2,1-C][1,2,4]Triazol-3-Methylamine. 3Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.