Description

7-Azaindole n-Oxide Hemihydrate is a high-purity heterocyclic building block and advanced pharmaceutical intermediate. This compound is valued for its unique nitrogen-oxygen fused ring system, which serves as a critical scaffold in modern medicinal chemistry for developing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, particularly in oncology and CNS drug development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile heterocyclic scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential fungicidal or insecticidal properties.
• Organic Synthesis: Employed in academic and industrial R&D for exploring novel organic reactions and synthesizing complex nitrogen-containing heterocycles.
• Material Science Precursor: Investigated for the development of specialty chemicals and advanced materials, such as ligands for catalysis or components in organic electronics.

Basic Information

Product Name	7-Azaindole n-Oxide Hemihydrate
CAS No.	1202864-61-6
Molecular Formula	C7H6N2O · ½H2O
Molecular Weight	138.14 g/mol (Anhydrous basis)
Synonyms	1H-Pyrrolo[2,3-b]pyridine 1-Oxide Hemihydrate; 7-Azaindole 1-Oxide Hemihydrate; 1H-1λ1-Pyrrolo[2,3-b]pyridine 1-Oxide Hemihydrate; 7-Aza-1-oxidanyl-indole Hemihydrate; Azaindole N-Oxide Sesquihydrate (common); 7-AIN-O Hemihydrate
EINECS	Contact for details

Quality Control

Our 7-Azaindole n-Oxide Hemihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	3.5 - 5.5% (Theoretical for hemihydrate: ~5.2%)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.