Description

(S)-Cyclobutyl(Phenyl)Methanamine Hydrochloride is a high-purity chiral amine hydrochloride salt, a critical building block in modern pharmaceutical synthesis. Its value lies in providing a defined stereocenter essential for creating active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D for life sciences.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the construction of complex molecular architectures for potential APIs targeting central nervous system (CNS) disorders, metabolic diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or resolving agent in stereoselective chemical transformations.
• Process Chemistry Development: Acts as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(S)-Cyclobutyl(Phenyl)Methanamine Hydrochloride
CAS No.	1202478-42-9
Molecular Formula	C11H15N·HCl
Molecular Weight	197.70 g/mol
Synonyms	(1S)-1-Cyclobutyl-1-phenylethanamine hydrochloride; (S)-1-Cyclobutyl-1-phenylethylamine hydrochloride; (S)-α-Methylcyclobutanemethylamine hydrochloride; (S)-Cyclobutyl(α-methylbenzyl)amine hydrochloride; (S)-1-Phenyl-1-cyclobutylethylamine hydrochloride; Benzenemethanamine, α-cyclobutyl-, (αS)-, hydrochloride; (S)-Cyclobutyl(phenyl)methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Cyclobutyl(Phenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98.0% by HPLC), chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere if the container is opened repeatedly. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.